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1

Entwicklung struktureller Template zur Mikrotubulihemmung durch weitgehende Abwandlung der Epothilon-Grundstruktur

Frédéric Cachoux, Thomas Isarno, Markus Wartmann, Karl-Heinz Altmann

Journal:

Angewandte Chemie

Year:

2005

Language:

german

File:

PDF, 126 KB

german, 2005

2

Scaffolds for Microtubule Inhibition through Extensive Modification of the Epothilone Template

Frédéric Cachoux, Thomas Isarno, Markus Wartmann, Karl-Heinz Altmann

Journal:

Angewandte Chemie International Edition

Year:

2005

Language:

english

File:

PDF, 123 KB

english, 2005

3

Total Synthesis and Biological Assessment of Benzimidazole-Based Analogues of Epothilone A: Ambivalent Effects on Cancer Cell Growth Inhibition

Fréderic Cachoux, Thomas Isarno, Markus Wartmann, Karl-Heinz Altmann

Journal:

Year:

2006

Language:

english

File:

PDF, 93 KB

english, 2006

4

ChemInform Abstract: First Total Synthesis of 11-Oxa Steroids.

Frederic Cachoux, Malika Ibrahim-Ouali, Maurice Santelli

Journal:

Year:

2000

File:

PDF, 29 KB

2000

5

ChemInform Abstract: First Total Synthesis of 11-Thia Steroids.

Frederic Cachoux, Malika Ibrahim-Ouali, Maurice Santelli

Journal:

Year:

2000

File:

PDF, 26 KB

2000

6

ChemInform Abstract: A New Efficient Synthesis of 11-Aza Steroids.

Frederic Cachoux, Malika Ibrahim-Ouali, Maurice Santelli

Journal:

Year:

2001

File:

PDF, 30 KB

2001

7

ChemInform Abstract: Simple Route to Cyclopentanol Derivatives.

Frederic Cachoux, Malika Ibrahim-Ouali, Maurice Santelli

Journal:

Year:

2002

File:

PDF, 32 KB

2002

8

Efficient Synthesis of the Bicyclo[5.3.0]decane System via Ring-Closing Metathesis.

Frederic Cachoux, Malika Ibrahim-Ouali, Maurice Santelli

Journal:

Year:

2003

File:

PDF, 105 KB

2003

9

Total Synthesis of 11-Azasteroids.

Frederic Cachoux, Malika Ibrahim-Ouali, Maurice Santelli

Journal:

Year:

2003

File:

PDF, 153 KB

2003

10

Synthesis of 4-Aza Analogues (I) of Epothilone D.

Frederic Cachoux, Franck Schaal, Antje Teichert, Trixie Wagner, Karl-Heinz Altmann

Journal:

Year:

2005

File:

PDF, 12 KB

2005

11

First total synthesis of 11-oxa steroids

Frédéric Cachoux, Malika Ibrahim-Ouali, Maurice Santelli

Journal:

Tetrahedron Letters

Year:

2000

Language:

english

File:

PDF, 95 KB

english, 2000

12

A new efficient synthesis of 11-aza steroids

Frédéric Cachoux, Malika Ibrahim-Ouali, Maurice Santelli

Journal:

Tetrahedron Letters

Year:

2001

Language:

english

File:

PDF, 99 KB

english, 2001

13

Cellular BRET assay suggests a conformational rearrangement of preformed TrkB/Shc complexes following BDNF-dependent activation

Luc De Vries, Frédéric Finana, Frédéric Cachoux, Bernard Vacher, Pierre Sokoloff, Didier Cussac

Journal:

Cellular Signalling

Year:

2010

Language:

english

File:

PDF, 858 KB

english, 2010

14

Epothilones as Lead Structures for the Synthesis-Based Discovery of New Chemotypes for Microtubule Stabilization

Feyen, Fabian, Cachoux, Frédéric, Gertsch, Jürg, Wartmann, Markus, Altmann, Karl-Heinz

Journal:

Accounts of Chemical Research

Year:

2008

Language:

english

File:

PDF, 331 KB

english, 2008

15

SIMPLE ROUTE TO CYCLOPENTANOL DERIVATIVES

Cachoux, Frédéric, Ibrahim-Ouali, Malika, Santelli, Maurice

Journal:

Synthetic Communications

Year:

2001

Language:

english

File:

PDF, 242 KB

english, 2001

16

TOTAL SYNTHESIS OF 11-AZASTEROIDS

Cachoux, Frédéric, Ibrahim-Ouali, Malika, Santelli, Maurice

Journal:

Synthetic Communications

Year:

2002

Language:

english

File:

PDF, 240 KB

english, 2002

17

Synthesis of 4-Aza Analogs of Epothilone D

Cachoux, Frédéric, Schaal, Franck, Teichert, Antje, Wagner, Trixie, Altmann, Karl-Heinz

Journal:

Year:

2004

Language:

english

File:

PDF, 118 KB

english, 2004

18

Total Synthesis and Biological Assessment of Cyclopropane-Based Epothilone Analogues - Modulation of Drug Efflux through Polarity Adjustments

Cachoux, Fréderic, Isarno, Thomas, Wartmann, Markus, Altmann, Karl-Heinz

Journal:

Year:

2006

Language:

english

File:

PDF, 88 KB

english, 2006

19

Natural Products as Leads for Anticancer Drug Discovery: Discovery of New Chemotypes of Microtubule Stabilizers through Reengineering of the Epothilone Scaffold

Altmann, Karl-Heinz, Cachoux, Frédéric, Feyen, Fabian, Gertsch, Jürg, Kuzniewski, Christian N., Wartmann, Markus

Journal:

CHIMIA International Journal for Chemistry

Year:

2010

Language:

english

File:

PDF, 373 KB

english, 2010